aldosterone
Eplerenone is a selective aldosterone antagonist.
依普利酮是选择性的醛甾酮拮抗药。
Aldosterone is the most important and powerful salt cortex hormone.
醛固酮是人体内最重要、作用最强的盐皮质激素。
Our findings may have insights of the non-hemodynamic action of aldosterone.
我们的实验为醛固酮的非血流动力学作用机制提供了一个体外证据。
Creatinine clearance was correlated directly with plasma aldosterone and inersely with renin.
肌酐清除率与血浆醛固酮浓度正相关，与肾素水平反相关。
The principal adrenocortical products are aldosterone, cortisol and dehydroepiandrosterone sulphate.
肾上腺皮质的主要产物为醛固酮、皮质醇和脱氢异雄酮硫酸盐。
The etiology of IHA,the main subtype,is related with increased abnormal aldosterone excreted factor and genovariation.
IHA为主要类型,发病与异常的促醛固酮分泌因子的增加及基因变异有关。
Renin angiotensin aldosterone(RAA) system was highly activated,while the blood pressure maintained normal.
肾素血管紧张素醛固酮(renin angiotensin aldosterone,RAA)系统活性明显升高。
The use of aldosterone antagonists for dilated cardiomyopathy improves levels of morbidity and mortality.
在扩张型心肌病治疗上加用醛固酮受体拮抗剂可改善发病率和死亡率。
Conclusion These studies indicate that kidney, liver and lung are able to produce aldosterone.
结论研究证明了肾脏、肝脏及肺脏能够合成醛固酮。
Conclusion The level of plasma aldosterone in the rat with pressure overload is increased.
结论压力负荷增加大鼠血浆醛固酮水平是升高的；
Objective To develop endolymphatic hydrops in both ears of guinea pigs by aldosterone.
目的豚鼠腹腔注射醛固酮建立膜迷路积水的动物模型。
Complementary and Incremental Mortality Risk Prediction by Cortisol and Aldosterone in Chronic Heart Failure.
关键词:心力衰竭；心血管疾病；一氧化氮；非洲美洲；试验
Eplerenon, a derivative of spironolactone, is the first selective aldosterone receptor antagonist.
依普利酮是一种螺内酯的衍生物,并且是第一种具有选择性的醛固酮受体拮抗剂。
Greene EL,Kren S,Hostetter TH.Role of aldosterone in the remnant kidney model in the rat.J Clin Invest.1996,98(4):1063.
邹军,杜学亮,蒋更如.不同程度慢性肾功能不全患者血醛固酮水平变化.放射免疫学杂志.2005,18(4):242.
The concept and meaning of clearance; Function and regulation of aldosterone; Secretion of H+、NH3、K+; Micturition reflex.
清除率的概念及测定意义；醛固酮的作用和调节；H+、NH3、K+分泌；排尿反射。
The effect of regressing myocardial fibrosis in the rat with CHF by captopril may be related to the decrease in plasma aldosterone level.
卡托普利逆转压力负荷增加大鼠心肌纤维化的作用可能与降低血浆醛固酮水平有关。
Significant correlation of body sodium and potassium with blood pressure (BP) may suggest a role for aldosterone in essential hypertension.
血压与体内钠钾代谢显著相关提示醛固酮在原发性高血压中起重要作用，醛固酮合成酶(CYP11B2)是醛固酮合成的关键酶，其基因被认为是原发性高血压的侯选基因。
The inhibition rates of plasma aldosterone after i. v.SLT were 16.1%, 28.9%, 15.4% and 5.2%, respectively, for those with APA, IHA, PAH and CA.
醛固酮瘤、特醛症、原发性肾上腺增生及醛固酮癌患者的静脉盐水负荷后血醛固酮的抑制率分别为16.1%、28.9%、15.4%和5.2%。
The plasma aldosterone of the model group increased (P＜0.01, vs sham group), while that of the captopril group decreased (P＜0.01, vs model group).
模型组血浆醛固酮水平较假手术组升高（P＜0.01），卡托普利组降低血浆醛固酮（P＜0.01）水平。
Conclusions Large dosage of spironolacton can aggravate renal fibrosis maybe through up-regulating level of renal aldosterone and its receptor.
结论 大剂量螺内酯可以加重高血压肾脏纤维化，可能是通过上调醛固酮及其受体表达实现的。
Aim The aldosterone receptor antagonist spironolactone has long been regarded as diuretic for the treatment of ascitis and portal hypertension.
目的 醛固酮受体拮抗剂螺内酯长期作为利尿剂用于减少腹水和降低门脉压的治疗，近年已初步证实螺内酯对CCl4所致大鼠肝纤维化有预防作用，但其作用机制尚不清楚。
The higher estimates encourage search for adrenal adenomas in patients with eleated ratios of plasma aldosterone to renin.
较高的评估促使人们在那些存在血醛固酮-肾素比率增高的患者中进行肾上腺腺瘤的研究。
In the nonca psule group, regardless of ACTH stimulation, no significant change was seen in the concentration of aldosterone and cortisol (P＞0.05).
未包膜组ACTH刺激前、后的醛固酮、皮质醇分泌量无显著差异（P>0.05）。
To investigate the relationship between gene polymorphism of aldosterone synthase (CYP11B2) and essential hypertension EH.Methods 1.
本研究旨在观察我国华南地区汉族人群醛固酮合成酶(CYP11B2)基因344C/T多态性与高血压病(EH)相关性。
The human body, for example, uses the hormones renin, angiotensin,aldosterone to retain or release tissue fluidsblood plasma.
例如，人体保留或释放组织液体和血浆而使用高血压蛋白原酶、血管紧张素、醛固酮等激素。
For the past few years,study of non-classic actions of aldosterone receptor bloker have been hot spot,especially eplerenone.
近年来,醛固酮受体阻滞剂的非传统作用已成为研究热点,尤其是依普利酮的研究。
Results Compared with the controls, the patients with PA had higher plasma and urinary aldosterone, lower serum potassium and upright PRA.
结果与对照组比较，原醛症组患者的血、尿醛固酮明显升高，而血钾及立位血浆肾素活性则低；
A disorder marked by excessive secretion of the hormone aldosterone, which can cause weakness, cardiac irregularities, and abnormally high blood pressure.
皮质醛酮增多症由于皮质醛酮激素分泌过量而导致的紊乱，可造成虚弱、心脏异常和异常高血压
Any of a group of steroid hormones,such as aldosterone,that are secreted by the adrenal cortex and regulate the balance of water and electrolytes in the body.
盐皮质激素一种类固醇荷尔蒙，如醛固酮，由肾上腺皮质分泌，调节体内水分和电解质的平衡。
The function of cardionatrin is to promote the secretion of sodium and water by kidney. The cardionatrin can reduce the release of aldosterone,ADH and renin.
肾素分泌作用:促进肾脏排钠排水。
Objective To confirm the effect of plasma aldosterone and reversing myocardial fibrosis of congestive heart failure(CHF) with captopril and to elucidate its possible mechanism.
目的进一步观察卡托普利对压力负荷增加大鼠血浆醛固酮的影响，探讨其抗心肌纤维化的可能作用机制。
Randomized aldactone evaluation study (RALES) showed that adding aldosterone antagonist in the treatment of heart failure may decrease 30% mortality of all causes.
随机螺内酯评估研究表明在心力衰竭治疗中加用醛甾酮拮抗药可使总死亡率降低30%。
The two groups continued to be cultured for 24 and 36 hours with ACTH stimulation. The concentrations of aldosterone and cortisol at 24 and 36 hours were detected respectively.
加入促肾上腺皮质激素 (ACTH)继续培养 2 4、36 h,用放免法分别测 ACTH刺激前后的醛固酮、皮质醇浓度。
Conclusion Spironolactone had some protective effects on pulmonary fibrosis, and aldosterone might play a role in the development of pulmonary fibrosis.
结论安体舒通对肺纤维化有一定的保护作用，醛固酮可能参与肺纤维化的发病过程。
Conclusion Aldosteronoma can be found in part of the patients with adrenal incidentaloma.Even if the aldosterone excess is minor, it may induce hypertension.
结论肾上腺意外瘤中有部分患者为醛固酮瘤，其醛固酮分泌轻度升高可导致高血压的发生；
This association of BMI is particularly evident in overweight-obese PH patients, and suggests a pathophysiological link between visceral adiposity and aldosterone secretion.
BMI的这种相关性在超重肥胖的高血压患者中尤其明显，提示在内脏型肥胖和醛固酮分泌之间有病理生理的联系。
In a person with CAH, the mixture of these hormones is wrong: The levels of both cortisol and aldosterone are too low, and the androgen level is too high.
罹患先天性肾上腺增生性肥大者，上述三种激素的综合平衡被打破：糖皮质激素和醛固酮分泌过少，而雄激素水平却太高。
We will mainly discuss the production of Aldosterone, the function of Aldosterone in CHF and the clinical application of Aldosterone Receptor Antagonist.
本文将对醛固酮的产生，醛固酮在心力衰竭过程中的作用以及醛固酮拮抗剂的临床应用作一个综述。
Further workup revealed a high serum aldosterone and a low serum renin, findings consistent with an aldosterone secreting adrenal adenoma (Conn's syndrome).
进一步检测发现醛固酮升高和肾素降低，结果与醛固酮分泌性肾上腺腺瘤(Conn综合症)一致。
Any of a group of steroid hormones, such as aldosterone, that are secreted by the adrenal cortex and regulate the balance of water and electrolytes in the body.
盐皮质激素一种类固醇荷尔蒙，如醛固酮，由肾上腺皮质分泌，调节体内水分和电解质的平衡
This article summarized the relationship between aldosterone and atrial fibrillation, the mechanism of this relationship and the clinical enlightenment.
文章综述了醛固酮与心房颤动的关系,醛固酮影响心房颤动的机制及相关的临床启示。
Objective To evaluate the influence of gene polymorphism of aldosterone synthase gene CYP11B2(-344T/C) on RAAS in Han Nationality essential hypertensive patients in Beijing.
摘要目的探讨醛固酮合成酶基因CYP11B2(-344T/C)多态性对北京汉族高血压患者肾素-血管紧张素-醛固酮(RAAS)系统的影响。
The aim of this study was to inestigate the relationships of plasma renin and aldosterone concentrations with renal outcomes after treatment of primary aldosteronism.
此项研究的目的就是探讨原发性醛固酮增多症治疗后血浆肾素水平和醛固酮浓度的关系。
Angiotensin also stimulates production of aldosterone, which leads to Na retention; excessive intracellular Na enhances the reactivity of vascular smooth muscle to sympathetic stimulation.
它还刺激醛固酮的产生，导致钠潴留；细胞内钠过多增强血管平滑肌对交感刺激的反应性。
Results Production of aldosterone in the kidney perfusate showed no change in adrenalectomized rats, but it was decreased in the kidney perfusate from rats pretreated with ACEI (perindopril).
研究表明肾脏离体灌注可以释放醛固酮、肾上腺切除不会改变肾灌注液中的醛固酮产量、而用ACEI培哚普利则可减少其产量；
Recently,positive results from two recent randomized controlled trials(RALES.EPHESUS)have led to renewed interest in the role of aldosterone receptor antagonists in the medical management of heart failure.
最近的2个随机对照试验(RALES和EPHESUS)得出了阳性结果,人们对醛固酮受体拮抗剂治疗心衰患者有了新的认识。
Objective To investigate whether aldosterone (Aldo) may be synthesized by glomerular mesangial cells and whether Aldo promotes the synthesis of fibronectin (FN) and type IV collagen in mesangial cells.
目的 证明肾脏系膜细胞能够自身合成醛固酮 ,并探讨醛固酮对系膜细胞细胞外基质生成的影响。 方法 用RT PCR法检测大鼠系膜细胞醛固酮合成酶CYP11B2mRNA表达 ,PCR产物存化后直接测序 ;
Objective To observe whether local aldosterone (ALDO) may be synthesized by hum an renal proximal tubular cell lines (HKC) and investigate whether endothelin-1 (ET-1) has effects on the production of local ALDO.
目的 观察人近端肾小管上皮细胞能否合成组织醛固酮(ALDO),以及内皮素-1 (ET-1)对该作用的影响。
Objective:Studing the changes of the serum angiotensin I (AI)angiotensin II (A II ) atrial natriuretic factor (ANF) and aldosterone(ALD) levels in patients with essential hypertension, and its clinicalsignificiance.
目的 :探讨原发性高血压 (EH)患者血清血管紧张素I(AI)、血管紧张素II(AII)、心钠素(ANF)和醛固酮 (ALD)水平的变化及其临床意义。
Objective:The aim of this study was to investigate the effects of extra spironolactone on the aldosterone (Aldo) level and heart function in patients with heart failure treated with angiotensin-converting enzyme inhibitor (ACEI).
目的 :观察慢性心力衰竭 (心衰 )患者应用血管紧张素转化酶抑制剂 (ACEI)治疗中加用醛固酮受体拮抗剂螺内酯对血浆醛固酮和心功能的影响。