benzodiazepine

It is useful to combine a benzodiazepine with an opioid.

苯二氮卓类与阿片类联合应用效果较好。

Crystal Structure and Conformational Analysis of a Substituted Tricyclic 1,5 - Benzodiazepine.

一个取代的三环1,5-苯并二氮杂(艹卓)的晶体结构和构象分析.

When used in combination with a benzodiazepine, the cardiovascular stimulation will be attenuated.

与苯二氮卓类药物连用心血管作用会减弱。

The drug cost was increasing year by year,while the percentage of benzodiazepine(BZ)hypnotics DDDs was decreasing.

镇静催眠药的年度金额逐年增长,苯二氮卓类药物仍占主要市场,年度药物DDDs总数的比例有下降趋势。

Midazolam, a sedative in the benzodiazepine group, and phenobarbital would help suppress Jeanna's brain activity.

镇静剂米诺达(midazolam,属于苯二氮平家族)与苯巴比妥(phenobarbital)则有助于抑制金娜脑子的活动。

The benzodiazepine antagonist flumazenil showed the lowest overall binding in milk and in casein solution.

巴比妥类药物拮抗剂氟马西尼在奶和酪蛋白溶液中结合能力最差。

In Taiwan, patients with a benzodiazepine overdose or abuse are commonly seen in clinical practice.

摘要台湾地区安眠药过量或滥用的病患,在临床上颇常见;

A tranquilizing drug,C15H11ClN2O2,related to benzodiazepine and used especially in the treatment of insomnia and alcohol withdrawal.

去甲羟基安定一种安定药,C15H11ClN2O2与苯二氮草有关,尤其用于失明症患者和戒烟者的治疗

A tranquilizing drug, C15H11ClN2O2, related to benzodiazepine and used especially in the treatment of insomnia and alcohol withdrawal.

去甲羟基安定一种安定药,C15H11ClN2O2与苯二氮草有关,尤其用于失明症患者和戒烟者的治疗

This mini-review includes the structure and function of GABAA receptor and the molecular mechanism of benzodiazepine tolerance and dependence.

本文简要综述了GABAA受体的功能结构及苯二氮类耐受性和依赖性的分子机制。

Between 5 per cent and 33 per cent of older people in the UK and North America are prescribed sleeping pills such as benzodiazepine.

很多60岁以上的老年人都受到了失眠症的困扰,这严重影响到了他们的生活质量。

Morphological studies revealed the existence of GABAA receptor, including its benzodiazepine binding site, and GABAB receptor in globus pallidus.

形态学研究揭示苍白球存在GABAA受体及其苯二氮卓结合位点和GABAB受体。

An autopsy concluded Biggs died from a combination of opiates and benzodiazepine, which his family said was prescribed for his bipolar disorder.

比格斯的尸检报告显示:他是死于服用过量的鸦片制剂和安息香重氮类安眠药。其家人说这些要是治疗狂躁症的必备药。

The research of antianxiety agents has gradually run to the pharmaceuticals acting on the other centrum and epibolic ancher from the single benzodiazepine and buspirone.

本文阐述了最新研制的几类抗焦虑药物的作用特点、可能的作用机理以及未来抗焦虑药物的发展趋势。

The MISPE method was demonstrated to be applicable to the analysis of diazepam metabolites and other benzodiazepine drugs, in addition to diazepam itself.

分子印迹固相萃取方法(MISPE)被证明了可用于地西泮代谢物和其他苯二氮卓类药物的分析,但除地西泮外。

A benzodiazepine drug, C16H14ClN3O, whose hydrochloride is used as an antianxiety drug and in the treatment of chronic alcoholism and alcohol withdrawal.

甲氨二氮?,利眠宁一种苯二氮?镇静药,C16H14ClN3O,其氢氯化物成分用作抗忧虑剂,并可用作慢性酒精中毒的治疗和戒酒

Methods The authors observed benzodiazepine receptors in amygdala-kindled rats with tolerance to anticonvulsant effect of clonazepam by using autoradiography.

方法采用放射自显影技术,观察了11只完全点燃大鼠对氯硝安定抗惊厥作用耐受及停药后大鼠脑内苯二氮?忱嗍芴宓谋浠?

Morphological studies revealed the existence of GABA(subscript A) receptor, including its benzodiazepine binding site, and GABAB receptor in globus pallidus.

形态学研究揭示,苍白球存在GABA(下标 A)、受体及其苯二氮卓结合位点和GABA(下标 B)受体。

In agreement with the in vitro effect, activation of GABAB receptor, GABAA receptor benzodiazepine binding site and blockade of GABA uptake cause rotation in behaving animal.

与离体实验结果相一致,激活苍白球GABAB受体和苯二氮卓结合位点及阻断GABA重摄取可引起整体动物旋转行为。

PurposeTo study the change of peripheral benzodiazepine receptors expression in liver of different period schistosomiasis mice with liver fibrosis and the effects of Huangqi on the expression of PBR in the liver.

研究血吸虫感染不同时期小鼠肝组织外周型苯二氮卓受体(PBR)表达水平,及中药黄芪对PBR表达的调控作用。

Results With clonazepam tolerance decreased binding of benzodiazepine receptors to[3H]flunitrazepam was found in some brain regions, while on day 7 of clonazepam discontinuation the binding increased.

=峁?大鼠耐受时某些脑区苯二氮?忱嗍芴迨?目减少,而停药7天时,一些脑区受体数目增多。

The trititated alpha-isobutyl-hydroxybenzyl alcohol(~3H-G018)was foundto be able to bind benzodiazepine(BZ)receptor on the rat brain membrane. The~(125)I labeled G-018 also had the similarbinding activity with this receptor.

氚标记的天麻甙元衍生物-a-异丁基对羟基苄醇(~3H-天018)作用于中枢苯二氮(艹卓)受体,~(125)I标记的天018仍然作用于该受体。

Results:Among these patients,the percentage of bipolar spectrum disorders (BPSD) was 12.8%,and the patients mostly treated with the new antidepressants(96.3%) and combined with benzodiazepine(95 2%).

结果:双相谱系障碍诊断率为12.8%,新型抗抑郁药应用比例96.3%,合并苯二氮艹卓类药物比例达952%,情感稳定剂使用率

Brain imaging studies indicate increased neuronal excitability and decreased density of benzodiazepine receptors in temporal (auditory) cortex but the source and mechanism of such changes are unknown.

大脑影像学研究表明(耳鸣患者)颞叶(听觉)皮层神经元兴奋性增高,也存在苯二氮卓受体密度减小,但这种转变的原因和机制未明。

Purine and Benzodiazepine analogues are considered of privileged structures in medicinal chemistry and often shown to possess a wide range of interesting pharmacological activities.

嘌呤 (purine) 和苯并二氮卓 (benzodiazepine) 都是被确定为“特权结构” (privileged structures) 的两类化合物,具有极其广泛的药理活性。

Different intravenous anesthetics, such as propofol, ketamine, benzodiazepine and barbiturates, which produce different levels of inhibition of inflammatory effects, are discussed in this article.

本篇文章同时讨论了各种静脉麻醉 剂在抑制发炎反应程度之差异,例如丙泊酚(Propofol)、K他命(ketamine)、苯二氮 平(benzodiazepines)、巴比妥盐(barbiturates)。

In addition to GABAB receptor, activation of GABAA receptor benzodiazepine binding site and blockade of GABA uptake change the activity of globus pallidus by prolonging the duration of GABA current.

除GABAB受体外,激活苍白球GABAA受体苯二氮卓结合位点及阻断GABA重摄取可延长GABA电流持续时间,从而改变苍白球神经元兴奋性。

Benzodiazepine receptor-binding inhibitor

苯并二氮类受体结合拮抗药

Peripheral benzodiazepine receptors

外周型苯二氮卓受体

Peripheral- type benzodiazepine receptor

外周型苯二氮卓类受体

peripheral-type benzodiazepine receptor

外周型苯二氮Zhuo类受体

non- benzodiazepine sedative hypnotic drugs

非苯二氮[艹卓]类催眠药

peripheral benzodiazepine receptor

外周苯二氮卓受体

Keywords Benzodiazepine;GABAA receptor;Tolerance;Seizure;Rat;

苯二氮(?)类;惊厥;受体;药物耐受性;大鼠;

Keywords Benzodiazepine;Seizure;GABAA receptor;Tolerance;

苯二氮革类;惊厥;受体;药物耐受性;

A CLINICAL ANALYSIS OF 56 CASES WITH HEROIN AND BENZODIAZEPINE MIXED DEPENDENCE

56例海洛因与苯二氮类混合依赖者临床分析

Study on the use of benzodiazepine among middle school students in Wuhan city

武汉市中学生使用苯二氮卓类药物的流行病学调查

an antianxiety agent (trade name Xanax) of the benzodiazepine class.

一种苯(并)二氮类抗焦虑的成分(商品名Xanax)。

Keywords Psychiatry;Schizophrenia;Benzodiazepine;Rational use of drugs;

关键词精神病学;精神分裂症;苯二氮(?)类药物;合理用药;

Effects of peripheral benzodiazepine receptors on seizure susceptibility in kainic acid-kindled rats

外周型苯二氮卓受体对海人酸点燃大鼠癫痫敏感性的影响

Changes of mitochondrial peripheral-type benzodiazepine receptor during rat live regeneration

大鼠肝再生过程中线粒体外周型苯二氮卓类受体的研究

Changes of peripheral-type benzodiazepine receptors in platelet membrane in patients with epilepsy

癫痫患者血小板膜外周型苯二氮卓受体的变化

Clinical observation of naloxone in treatment of acute poisoning due to benzodiazepine

纳洛酮治疗苯二氮蕈类药物急性中毒临床观察

Keywords Flumazenil;Epilepsy;Epileptogenic focus;EEG;Benzodiazepine receptor antagonist;Surgery;

氟马西尼;诱发;癫痫;癫痫灶;脑电图;苯二氮卓受体拮抗剂;手术;

Keywords anxiolytic effect;peripheral benzodiazepine receptor;indo derivative;progesterone;

抗焦虑作用;外周型苯二氮卓受体;吲哚衍生物;孕酮;

Keywords midazolam;peripheral benzodiazepine receptor;hypoxia/reoxygenation injury;cardiac myocyte;apoptosis;

咪达唑仑;外周型苯二氮卓受体;缺氧复氧损伤;心肌细胞;细胞凋亡;

Keywords brain ageing;epilepsy;mitochondria;synaptosomes;peripheral benzodiazepine receptors;

脑老化;癫痫;线粒体;突触体;外周型苯二氮卓受体;

Keywords Post-menopausal women;Hormone replacement therapy;Peripheral Benzodiazepine receptors (PBR);Platelet;

绝经后妇女;激素替代疗法;外周型苯二氮卓受体;血小板;

Keywords brain;aging;platelets;mitochondria;peripheral benzodiazepine receptors;

脑;衰老;血小板;线粒体;外周型苯二氮卓受体;

Keywords Psychiatric outpatients;Long-term use;Benzodiazepine;Clinical features;

关键词精神科门诊病人;长期应用;苯二氮类药物;临床特征;