histone
The histone code will not be easy to crack.
组织蛋白的密码不是那么容易破解的。
A nucleoprotein whose protein component is a histone.
核组蛋白蛋白成分是组蛋白的核蛋白
A nucleoprotein whose protein componentis a histone.
核组蛋白蛋白成分是组蛋白的核蛋白。
Study on histone acetylation in myoblast cultures of DMD chicken embryo.
进行性肌营养不良鸡胚成肌细胞组蛋白的乙酰化研究。
Histone acetylation/deacetylation is closely related to the regulation of gene.
组蛋白乙酰化/去乙酰化与基因调控密切相关。
Histone lysine methylation plays a key role in epigenetic regulation.
摘要组蛋白赖氨酸的甲基化在表观遗传调控中起着关键作用。
Histone modifications are implicated in influencing gene expression.
组蛋白修饰与影响基因表达有关。
Histone deacetylase inhibitors had been used to treat cancer and leukemia.
组蛋白去乙酰化酶抑制剂已经越来越多的被用于治疗肿瘤和白血病。
The chromatin remodeling and histone acetylation were associated with transcription activation.
真核基因活化与染色质的重建及组蛋白的乙酰化相关。
Su(ar)3-9 proteins attach methyl groups to the histone labeled H3 at its ninth amino acid residue, which is a lysine.
9蛋白将甲基加在组蛋白H3的第九位氨基酸残基，也就是赖氨酸残基上，从而使H3组蛋白贴上了个标签。
The pharmacological actions of histone deacetylase inhibitors and their potential clinical uses were reviewed.
综述了组蛋白去乙酰酶抑制剂的药理作用及其临床应用前景。
Effective inhibitor of protein kinase C (PKC)-catalyzed histone phosphorylation.
有效的PKC催化组蛋白磷酸化抑制剂。
Z associates with functional regulatory elements, and CTCF marks boundaries of histone methylation domains.
Z和功能调控元件相关，CTCF标记组蛋白甲基化区域边界。
The level of histone acetylation plays an important role in progression, proliferation and differentiation of leukemia.
组蛋白乙酰化水平的异常在白血病的发展、增殖和分化中起着很重要的作用。
The hypothesis of "Histone code" suggests an existing way of program information of eukaryotic gene control.
摘要“组蛋白编码”假说提示了真核生物基因调控的程序性信息的存在方式。
In addition, histone exchange reveals new changing mechanism of DNA-histone interaction.
并且，组蛋白替换揭示了DNA-组蛋白相互作用变化的一种新的机制。
One example of such modifications is histone ubiquitination, which occurs predominately on histone H2A and H2B.
其中一种修饰作用就是发生于组蛋白H2A和H2B的泛素化作用。
One such histone demethylase, JHDM1B, has been suggested to be a tumour suppressor.
这样一种组蛋白去甲基化酶JHDM1B曾被认为是一个肿瘤抑制因子。
Chromosome banding patterns are correlated with unique patterns of histone modifications.
染色体带型和组蛋白修饰的特有模式相关。
Histone modifications such as lysine methylation affect chromatin structure and gene expression.
组蛋白修饰（如赖胺酸残迹的甲基化）能影响染色质结构和基因表达。
Nucleosome Assembly Protein 1 (NAP1) is considered to be a histone chaperone involved in nucleosome assembly.
核小体组装蛋白1（NAP1）被认为是参与到核小体组装过程中的组蛋白分子伴侣。
Arginine An AMINO ACID found especially in the histone proteins that surround DNA in chromosomes.
精氨酸：在染色体中与DNA非特异性结合的组蛋白中发现的一种氨基酸。
Histone deacetylase 3 (HDAC3) has been implicated to play roles in governing cell proliferation.
组蛋白去乙酰化酶3 （HDAC3）在细胞增殖的过程中发挥着重要作用。
In eukaryotic cells, DNA is located in nucleolus in the form of chromatin by combining with histone proteins.
在真核生物中，DNA分子缠绕在组蛋白上形成染色质保存在细胞的细胞核中。
DNA has negative charges and histone has positive ones.So the interaction between them is coulombic force.
DNA分子带强负电而组蛋白则带正电，库仑相互作用起主要的作用。
Sensitive assay system for inhibitor screening and kinetic assays of HDAC1 (histone deacetylase 1).
一种用于抑制剂筛选和HDAC1动力学检测的敏感检测系统。
Recently, Strahl and Allis's proposition of the existence of "histone code" makes the investigation of h...
该学说表明,组蛋白氨基末端的多样化修饰扩充了遗传密码的信息库。
The acetylation of histone is related to gene expression and regulation,which takes part in the pathological courses of all kinds of lung diseases.
组蛋白乙酰化修饰与基因的表达调控相关,参与了各种肺部疾病的病变过程。
Depletion of maternal BRG1 did not affect global levels of histone acetylation, whereas dimethyl-H3K4 levels were reduced.
BRG1蛋白的缺失没有影响组蛋白乙酰化的整体水平，但是二甲基H3K4的水平有所降低。
HIR/HIRA,encoded by Hir/Hira(histone regulation) genes,were identified as negative regulators of histone gene expression.
H ir/H ira基因产物是组蛋白基因表达的一种负调节因子,其在果蝇发育过程中的作用还没有得到确认.
Nucleosome assembly protein 1 (NAP1) is conserved from yeast to human and facilitates in vitro the assembly of nucleosomes as a histone chaperone.
核小体组装蛋白(Nucleosome Assembly Protein 1, NAP1)是真核生物中非常保守的、在体外能够促进核小体组装的一种组蛋白分子伴侣。
DNA methylation has an important role in transcriptional regulation, togethering with histone modification and chromatin remodeling.
DNA甲基化在基因转录过程中扮有重要角色，并与组蛋白修饰、染色质构型重塑共同参与转录调控。
Recently, research on histone variants is not only a new hotspot in epigenetics, but also a new annotation of "histone code".
对组蛋白变体的研究是近年来表观遗传学新的研究热点，也是对“组蛋白密码”的新的诠释。
With intensive study, the mechanism of histone deacetylase inhibitors in leukemia has been paid more and more attention.
随着对组蛋白乙酰化的深入研究,组蛋白去乙酰化酶抑制剂在白血病中的作用机制越来越受到人们的关注。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
Histone is the nucleus of chromatin,the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心,其尾部的共价修饰组成组蛋白密码,调节许多生物学事件。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰,在基因的表观遗传转录调控中起着关键的作用。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
在染色体中，SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
"Histone: Any of a class of rather simple proteins occurring in cell nuclei and in combination with DNA to form nucleoproteins.
组蛋白：任何一种存在于细胞核内或者与去氧核糖核酸结合成核蛋白的相当简单的蛋白质。
We will further investigate the relationship of histone modification and promoter methylation on the expression of TFPI-2.
今后，我们将在表观遗传层面对TFPI-2基因的修饰和相关组蛋白的修饰进行深入研究。
Histone deacetylase (HDAC) greatly affects the chromatin topology and gene expression,and HDAC can be a new strategy in human cancer or tumour therapy.
组蛋白去乙酰化酶(HDAC)对染色质分布和基因调节起着重要的作用,也是治疗癌症和其它疾病的新靶点。
Histone 3 methylated at lysine 4(H3K4),one type of these covalent modifications,is associated with active chromatin and gene expression.
组蛋白H3第4赖氨酸的甲基化作为共价修饰的方式之一,可以调控基因的转录激活。
SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing.
Su(var)3-9家族的SDP专一甲基化组蛋白3第9位赖氨酸(H3K9),从而导致基因沉默(gene silencing)。
We numerically simulate the interaction between DNA and a histone.And we get the nucleosome structure.DNA wraps around histone about 2 loops.
在适当的参数条件下，得到了合理的结果，即DNA能够缠绕组蛋白约两圈形成准核小体结构。
In prokaryotes the nuclear material is simply a circular strand of DNA, not complexed with histone proteins, and cell division is amitotic.
在原核生物中，核物质仅是一个简单的环状DNA，而不与组蛋白结合，并且细胞为无丝分裂。
The massive researches on histone methyltransferase and effector proteins in recent years have increased our understanding of H3K4 methylation.
随着对组蛋白甲基化转移酶及相关作用蛋白研究的深入,人们对组蛋白H3第4赖氨酸的甲基化的功能也有了更深的了解。
Title： Cloning, expression and transcriptional activity of Bm-mof, an MYST histone acetyltransferase gene in the silkworm, Bombyx mori L.
关键词：家蚕;MYST组蛋白乙酰转移酶;克隆;序列分析;表达谱
S is DNA synthesis phase and G2 is DNA synthesis anaphase in which tubulin is synthesized mostly and the synthesis of RNA and histone decreases.
G2 期为DNA 合成后期，主要合成微管蛋白等，RNA 和组蛋白合成减少。
There are two kinds of molecular containing histone deacetylase activity: One is homology with yeast RPD3,and another is not homology with yeast RPD3.
含有组蛋白脱乙酰化酶活性的分子有两类:一类是与酵母RPD3同源的分子,另一类是与RPD3不同源的分子。
This was further supported by the observation that the increasing effect of HS4 was counteracted by histone acetyltransferase inhibitors.
通过加入组蛋白乙酰基转移酶抑制剂，我们观察到HS4的增强作用受到了抑制，这使我们更加确信上述的观点。